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This search was complemented by hand searches of the bibliographies of original and review articles. A total of 17 studies were included in this meta-analysis. The risk of SSI was reduced by 30% with sub-therapeutic prophylaxis in elective colorectal surgery (risk ratio = 0.69, 95% confidence interval [CI]: 0.56-0.85; P = 0.0003). However, sub-therapeutic prophylaxis did not reduce SSI in emergency operations (risk ratio = 0.77, 95% CI: 0.60-0.99; P = 0.04). Sub-therapeutic prophylaxis should be avoided in emergency colorectal surgery. However, in elective colorectal surgery, the risk of infection can be reduced by sub-therapeutic prophylaxis. We agree with the majority of authors who state that a positive history of an adenoma or a CRC is not associated with a high risk of a CRC recurrence. This is the case for almost all authors (except for Boonstra et al. [@pone.0063250-Boonstra1]), and is in line with several studies which showed that patients with a previous adenoma or a CRC recurrence, who are at a high risk of an early CRC recurrence, may benefit from a stricter surveillance program [@pone.0063250-Rudolph1]. In this study, we observed a negative association between CRC recurrence and the number of previous adenomas. Our findings are supported by the study of Boonstra et al., which reported a significantly increased risk of a CRC recurrence in patients with one or more adenomas compared to patients without adenomas [@pone.0063250-Boonstra1]. In contrast, Rudolph et al. [@pone.006 What's New in the AutoCAD? Autodesk Revit 2019 19: For the first time in Revit history, you can use the same Autodesk® ArcGIS® integration toolset you use in AutoCAD and AutoCAD LT to quickly and easily import or export information into and out of Autodesk® Revit®. (video: 2:40 min.) 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